Marcaine Spinal

Generic Name: bupivacaine (bue PIV a kane)

Brand Names: Marcaine HCl, Marcaine Spinal, Sensorcaine, Sensorcaine-MPF

What is Marcaine Spinal (bupivacaine)?

Bupivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

Bupivacaine is used as a local (in only one area) anesthetic for a spinal block.

Bupivacaine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Marcaine Spinal (bupivacaine)?

You should not receive bupivacaine if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving this medication, tell your doctor if you have liver disease, a bleeding or blood clotting disorder, syphilis, polio, a brain or spinal cord tumor, chronic back pain, a headache, low or high blood pressure, a curved spine, or arthritis.

This medication can cause numbness over a large portion of your body. Take care to avoid injury before the feeling has returned completely.

Spinal numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from bupivacaine.

What should I discuss with my health care provider before receiving Marcaine Spinal (bupivacaine)?

You should not receive bupivacaine if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving bupivacaine, tell your doctor if you are allergic to any drugs, or if you have:

• 
  

  liver disease;

  
  


• 
  

  a bleeding or blood clotting disorder;

  
  


• 
  

  syphilis, polio, or a brain or spinal cord tumor;

  
  


• 
  

  chronic back pain or a headache;

  
  


• 
  

  low or high blood pressure;

  
  


• 
  

  curvature of the spine; or

  
  


• 
  

  arthritis.

  
  

If you have any of these conditions, you may not be able to receive bupivacaine, or you may need dosage adjustments or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Before you receive bupivacaine, tell your doctor if you are pregnant. Bupivacaine can pass into breast milk and may harm a nursing baby. Before you receive bupivacaine, tell your doctor if you are breast-feeding a baby.

How is bupivacaine given?

Bupivacaine is given as an injection placed into an area of your lower back near your spine. You will receive this injection in a hospital or surgical setting.

Spinal numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from bupivacaine.

What happens if I miss a dose?

Since bupivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

Tell your caregivers right away if you think you have received too much of this medicine.

Overdose symptoms may include extreme drowsiness, fainting, seizure (convulsions), shallow breathing, or breathing that stops.

What should I avoid after receiving Marcaine Spinal (bupivacaine)?

This medication can cause numbness over a large portion of your body. Take care to avoid injury before the feeling has returned completely.

Marcaine Spinal (bupivacaine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have any of these serious side effects:

• 
  

  weak or shallow breathing;

  
  


• 
  

  fast heart rate, gasping, feeling unusually hot;

  
  


• 
  

  slow heart rate, weak pulse;

  
  


• 
  

  feeling restless or anxious, ringing in the ears, metallic taste, speech problems, numbness or tingling around your mouth, tremors, feeling light-headed, or fainting; or

  
  


• 
  

  problems with urination.

  
  

Less serious side effects include:

• 
  

  nausea, vomiting;

  
  


• 
  

  headache, back pain;

  
  


• 
  

  dizziness;

  
  


• 
  

  or problems with sexual function.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Marcaine Spinal (bupivacaine)?

Before receiving bupivacaine, tell your doctor if you are using any of the following drugs:

• 
  

  a blood thinner such as warfarin (Coumadin);

  
  


• 
  

  ergot medicine such as ergotamine (Ergomar, Cafergot), dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), or methylergonovine (Methergine);

  
  


• 
  

  an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or

  
  


• 
  

  antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

  
  

If you are using any of these drugs, you may not be able to receive bupivacaine, or you may need dose adjustments or extra monitoring during anesthesia.

This list is not complete and there may be other drugs that can interact with bupivacaine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Marcaine Spinal resources

• Marcaine Spinal Side Effects (in more detail)
• Marcaine Spinal Use in Pregnancy & Breastfeeding
• Marcaine Spinal Drug Interactions
• Marcaine Spinal Support Group
• 0 Reviews for Marcaine Spinal - Add your own review/rating

• Marcaine Spinal Prescribing Information (FDA)


• Marcaine Spinal Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• Bupivacaine Prescribing Information (FDA)


• Bupivacaine Solution MedFacts Consumer Leaflet (Wolters Kluwer)


• Bupivacaine Hydrochloride Monograph (AHFS DI)


• Sensorcaine Prescribing Information (FDA)

Compare Marcaine Spinal with other medications

• Cesarean Section
• Local Anesthesia

Where can I get more information?

• Your doctor or pharmacist can provide more information about bupivacaine.

See also: Marcaine Spinal side effects (in more detail)

Coal Tar

Generic Name: coal tar topical (KOL TAR TOP ik al)

Brand Names: Balnetar, Betatar Gel, Coal Tar, Cutar, Denorex, Denorex Dry Scalp, Denorex Extra Strength, Denorex Medicated Shampoo and Conditioner, DHS Tar Shampoo, Doak Tar, Doak Tar Oil, Elta Tar, Fototar, G-TAR, Ionil T, Ionil T Plus, MG 217 Psoriasis, MG217 Medicated Tar, Neutrogena T/Derm, Neutrogena T/Gel, Neutrogena T/Gel Extra Strength, Oxipor VHC, PC Tar, Pentrax, Pentrax Gold, Polytar, Psoriasin, Psorigel, T/Gel Conditioner, Tegrin Medicated, Tegrin Medicated Soap, Therapeutic, Theraplex T, Zetar

What is coal tar?

Coal tar is a by-product of coal processing.

Coal tar topical (for the skin) is used to treat the skin symptoms of psoriasis, including dryness, redness, flaking, scaling, and itching. Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.

Coal tar may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about coal tar?

You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.

Do not use coal tar to treat the skin of your groin or rectal area.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.

Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.

What should I discuss with my health care provider before using coal tar?

You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether coal tar passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Coal tar products may contain lanolin, mineral oil, or other emulsifiers. Check the label of any coal tar product you are using. Talk with your doctor before using coal tar if you are allergic to any of the ingredients.

How should I use coal tar?

Use this medication as directed on the label, or as your doctor has prescribed. Do not use the medication in larger amounts or for longer than recommended.

Apply coal tar cream, lotion, ointment, or solution according the directions on the medication label. Some forms of coal tar may be applied 1 to 4 times per day.

To use coal tar bath oil, pour 1 to 3 capfuls into a warm bath before bathing. The oil can make the bathtub slippery. Take care to avoid a fall.

Shake the coal tar shampoo well just before each use. Use enough shampoo to create a rich lather. Massage the shampoo into your scalp and rinse thoroughly. Apply the shampoo a second time and leave it on your scalp for 5 minutes. Rinse thoroughly. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.

Coal tar shampoo may discolor blond or colored hair. This effect is usually temporarily.

Some forms of coal tar can stain fabric or other surfaces.

Store coal tar at room temperature away from moisture and heat. Keep the medicine tightly closed with not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a coal tar overdose are not known.

What should I avoid while using coal tar?

Avoid getting this medication in your eyes. If this does occur, rinse with water.

Do not use coal tar to treat the skin of your groin or rectal area.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result.

Coal tar side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin.

Less serious side effects may include mild skin irritation or skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect coal tar?

Do not use coal tar together with other psoriasis medications unless your doctor tells you to.

There may be other drugs that can interact with coal tar. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Coal Tar resources

• Coal Tar Side Effects (in more detail)
• Coal Tar Use in Pregnancy & Breastfeeding
• Coal Tar Support Group
• 4 Reviews for Coal Tar - Add your own review/rating

• Coal Tar Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Denorex Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)


• Doak Tar Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)


• Fototar Ointment MedFacts Consumer Leaflet (Wolters Kluwer)


• MG217 Medicated Tar Lotion MedFacts Consumer Leaflet (Wolters Kluwer)


• Psoriasin Prescribing Information (FDA)


• coal tar Topical Advanced Consumer (Micromedex) - Includes Dosage Information

Compare Coal Tar with other medications

• Dermatitis
• Psoriasis
• Seborrheic Dermatitis

Where can I get more information?

• Your pharmacist can provide more information about coal tar.

See also: Coal Tar side effects (in more detail)

Triprolidine Suspension

Pronunciation: trye-PROE-li-deen
Generic Name: Triprolidine
Brand Name: Zymine XR

Triprolidine Suspension is used for:

Preventing or treating symptoms of hay fever or other allergies, such as runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes. It may also be used for other conditions as determined by your doctor.

Triprolidine Suspension is an antihistamine. It works by blocking the action of histamine, reducing the symptoms of an allergic reaction.

Do NOT use Triprolidine Suspension if:

• you are allergic to any ingredient in Triprolidine Suspension or other similar medicines


• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Triprolidine Suspension:

Some medical conditions may interact with Triprolidine Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat


• if you have a history of asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis; lung problems (eg, emphysema); shortness of breath; sleep apnea; heart blood vessel problems; stroke; seizures; a blockage of your stomach, intestine, or bladder; difficulty urinating; diabetes; ulcers; an enlarged prostate or other prostate problems; glaucoma; heart problems; high blood pressure; porphyria; phenylketonuria; or an overactive thyroid

Some MEDICINES MAY INTERACT with Triprolidine Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur


• Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Triprolidine Suspension's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Triprolidine Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Triprolidine Suspension:

Use Triprolidine Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Triprolidine Suspension by mouth with or without food.


• Shake well before each use.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Triprolidine Suspension and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Triprolidine Suspension.

Important safety information:

• Triprolidine Suspension may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Triprolidine Suspension. Using Triprolidine Suspension alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Triprolidine Suspension. Triprolidine Suspension will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.


• Triprolidine Suspension may cause dizziness. Alcohol, hot weather, exercise, and fever can increase this effect. To prevent it, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness.


• Do not become overheated in hot weather or during exercise or other activities since heatstroke may occur.


• If you are scheduled for allergy skin testing, check with your doctor. You may need to stop taking Triprolidine Suspension for several days before the test because it may decrease your response to the skin tests.


• Phenylketonuria patients - Triprolidine Suspension contains phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.


• If your symptoms do not get better, or if they get worse, or if they occur with a fever, contact your doctor.


• Use Triprolidine Suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.


• Triprolidine Suspension should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Triprolidine Suspension while you are pregnant. Triprolidine Suspension is found in breast milk. Do not breast-feed while you are taking Triprolidine Suspension.

Possible side effects of Triprolidine Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, throat, and nose; excitability; loss of appetite; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; decreased alertness; fast heartbeat or pounding in the chest; hallucinations; tremor; trouble urinating; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Triprolidine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.

Proper storage of Triprolidine Suspension:

Store Triprolidine Suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Triprolidine Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Triprolidine Suspension, please talk with your doctor, pharmacist, or other health care provider.


• Triprolidine Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Triprolidine Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Triprolidine resources

• Triprolidine Side Effects (in more detail)
• Triprolidine Use in Pregnancy & Breastfeeding
• Triprolidine Drug Interactions
• Triprolidine Support Group
• 1 Review for Triprolidine - Add your own review/rating

Compare Triprolidine with other medications

• Allergic Urticaria
• Allergies
• Conjunctivitis, Allergic
• Eye Redness/Itching
• Hay Fever
• Rhinorrhea

E.E.S. 400

Generic Name: erythromycin (Oral route, Parenteral route)

e-rith-roe-MYE-sin

Commonly used brand name(s)

In the U.S.

• E.E.S. 200


• E.E.S. 400


• E.E.S. Granules


• Eryped


• Eryped 200


• Eryped 400


• Erythrocin


• Erythrocin Stearate


• Ilosone

In Canada

• E.E.S. 100


• Ees 200


• Novo-Rythro Estolate Suspension


• Novo-Rythro Ethyl Succinate Suspension


• Novo-Rythro Stearate

Available Dosage Forms:

• Suspension


• Powder for Suspension


• Tablet


• Tablet, Chewable


• Capsule

Uses For E.E.S. 400

Erythromycins are used to treat many kinds of infections. Erythromycins are also used to prevent "strep" infections in patients with a history of rheumatic heart disease who may be allergic to penicillin.

These medicines may also be used to treat Legionnaires' disease and for other problems as determined by your doctor. They will not work for colds, flu, or other virus infections.

Erythromycins are available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, erythromycins are used in certain patients with the following medical conditions:

• Acne


• Actinomycosis


• Anthrax


• Chancroid


• Gastroparesis


• Lyme disease


• Lymphogranuloma venereum


• Relapsing fever

Before Using E.E.S. 400

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems in children than it does in adults.

Geriatric

This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults. However, older adults may be at increased risk of hearing loss, especially if they are taking high doses of erythromycin and/or have kidney or liver disease.

Pregnancy

Erythromycin estolate has caused side effects involving the liver in some pregnant women. However, none of the erythromycins has been shown to cause birth defects or other problems in human babies.

Breast Feeding

Erythromycins pass into the breast milk. However, erythromycins have not been shown to cause problems in nursing babies.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Heart disease—High doses of erythromycin may increase the chance of side effects in patients with a history of an irregular heartbeat.

• Liver disease—Erythromycins, especially erythromycin estolate, may increase the chance of side effects involving the liver.

• Loss of hearing—High doses of erythromycins may, on rare occasion, cause hearing loss, especially if you have kidney or liver disease.

Proper Use of erythromycin

This section provides information on the proper use of a number of products that contain erythromycin. It may not be specific to E.E.S. 400. Please read with care.

Generally, erythromycins are best taken with a full glass (8 ounces) of water on an empty stomach (at least 1 hour before or 2 hours after meals). If stomach upset occurs, these medicines may be taken with food. If you have questions about the erythromycin medicine you are taking, check with your health care professional.

For patients taking the oral liquid form of this medicine:

• This medicine is to be taken by mouth even if it comes in a dropper bottle. If this medicine does not come in a dropper bottle, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid


• Do not use after the expiration date on the label. The medicine may not work properly after that date. Check with your pharmacist if you have any questions about this.

For patients taking the chewable tablet form of this medicine:

• Tablets must be chewed or crushed before they are swallowed.

For patients taking the delayed-release capsule form (with enteric-coated pellets) or the delayed-release tablet form of this medicine:

• Swallow capsules or tablets whole. Do not break or crush. If you are not sure about which type of capsule or tablet you are taking, check with your pharmacist.

To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. If you have a "strep" infection, you should keep taking this medicine for at least 10 days. This is especially important in "strep" infections. Serious heart problems could develop later if your infection is not cleared up completely. Also, if you stop taking this medicine too soon, your symptoms may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times day and night. For example, if you are to take 4 doses a day, the doses should be spaced about 6 hours apart. If this interferes with your sleep or other daily activities, or if you need help in planning the best times to take your medicine, check with your health care professional.

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For erythromycin base


• For oral dosage forms (capsules, tablets):
  
  • For treatment of infections:
    
    • Adults and teenagers—250 to 500 milligrams (mg) two to four times a day.
    
    
    • Children—Dose is based on body weight. The usual dose is 7.5 to 12.5 mg per kilogram (kg) (3.4 to 5.6 mg per pound) of body weight four times a day, or 15 to 25 mg per kg (6.8 to 11.4 mg per pound) of body weight two times a day.
    
    
  
  
  • For prevention of heart infections:
    
    • Adults and teenagers—Take 1 gram two hours before your dental appointment or surgery, then 500 mg six hours after taking the first dose.
    
    
    • Children—Dose is based on body weight. The usual dose is 20 mg per kg (9.1 mg per pound) of body weight two hours before the dental appointment or surgery, then 10 mg per kg (4.5 mg per pound) of body weight six hours after taking the first dose.
    
    
  
  

• For erythromycin estolate


• For oral dosage forms (capsules, oral suspension, tablets):
  
  • For treatment of infections:
    
    • Adults and teenagers—250 to 500 milligrams (mg) two to four times a day.
    
    
    • Children—Dose is based on body weight. The usual dose is 7.5 to 12.5 mg per kilogram (kg) (3.4 to 5.6 mg per pound) of body weight four times a day, or 15 to 25 mg per kg (6.8 to 11.4 mg per pound) of body weight two times a day.
    
    
  
  
  • For prevention of heart infections:
    
    • Adults and teenagers—Take 1 gram two hours before your dental appointment or surgery, then 500 mg six hours after taking the first dose.
    
    
    • Children—Dose is based on body weight. The usual dose is 20 mg per kg (9.1 mg per pound) of body weight two hours before the dental appointment or surgery, then 10 mg per kg (4.5 mg per pound) of body weight six hours after taking the first dose.
    
    
  
  

• For erythromycin ethylsuccinate


• For oral dosage forms (oral suspension, tablets):
  
  • For treatment of infections:
    
    • Adults and teenagers—400 to 800 milligrams (mg) two to four times a day.
    
    
    • Children—Dose is based on body weight. The usual dose is 7.5 to 12.5 mg per kilogram (kg) (3.4 to 5.6 mg per pound) of body weight four times a day, or 15 to 25 mg per kg (6.8 to 11.4 mg per pound) of body weight two times a day.
    
    
  
  
  • For prevention of heart infections:
    
    • Adults and teenagers—Take 1.6 grams two hours before your dental appointment or surgery, then 800 mg six hours after taking the first dose.
    
    
    • Children—Dose is based on body weight. The usual dose is 20 mg per kg (9.1 mg per pound) of body weight two hours before the dental appointment or surgery, then 10 mg per kg (4.5 mg per pound) of body weight six hours after taking the first dose.
    
    
  
  

• For erythromycin gluceptate


• For injection dosage forms:
  
  • For treatment of infections:
    
    • Adults and teenagers—250 to 500 milligrams (mg) injected into a vein every six hours; or 3.75 to 5 mg per kilogram (kg) (1.7 to 2.3 mg per pound) of body weight injected into a vein every six hours.
    
    
    • Children—Dose is based on body weight. The usual dose is 3.75 to 5 mg per kg (1.7 to 2.3 mg per pound) of body weight injected into a vein every six hours.
    
    
  
  

• For erythromycin lactobionate


• For injection dosage forms:
  
  • For treatment of infections:
    
    • Adults and teenagers—250 to 500 milligrams (mg) injected into a vein every six hours; or 3.75 to 5 mg per kilogram (kg) (1.7 to 2.3 mg per pound) of body weight injected into a vein every six hours.
    
    
    • Children—Dose is based on body weight. The usual dose is 3.75 to 5 mg per kg (1.7 to 2.3 mg per pound) of body weight injected into a vein every six hours.
    
    
  
  

• For erythromycin stearate


• For oral dosage forms (oral suspension, tablets):
  
  • For treatment of infections:
    
    • Adults and teenagers—250 to 500 milligrams (mg) two to four times a day.
    
    
    • Children—Dose is based on body weight. The usual dose is 7.5 to 12.5 mg per kilogram (kg) (3.4 to 5.6 mg per pound) of body weight four times a day; or 15 to 25 mg per kg (6.8 to 11.4 mg per pound) of body weight two times a day.
    
    
  
  
  • For prevention of heart infections:
    
    • Adults and teenagers—Take 1 gram two hours before your dental appointment or surgery, then 500 mg six hours after taking the first dose.
    
    
    • Children—Dose is based on body weight. The usual dose is 20 mg per kg (9.1 mg per pound) of body weight two hours before the dental appointment or surgery, then 10 mg per kg (4.5 mg per pound) of body weight six hours after taking the first dose.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using E.E.S. 400

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

E.E.S. 400 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Fever


• nausea


• skin rash, redness, or itching


• stomach pain (severe)


• unusual tiredness or weakness


• vomiting


• yellow eyes or skin–with erythromycin estolate (rare with other erythromycins)

Less common - with erythromycin injection only

• Pain, swelling, or redness at place of injection

Rare

• Fainting (repeated)


• irregular or slow heartbeat


• loss of hearing (temporary)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Abdominal or stomach cramping and discomfort


• diarrhea


• nausea or vomiting

Less common

• Sore mouth or tongue


• vaginal itching and discharge

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More E.E.S. 400 resources

• E.E.S. 400 Use in Pregnancy & Breastfeeding
• Drug Images
• E.E.S. 400 Drug Interactions
• E.E.S. 400 Support Group
• 13 Reviews for E.E.S. 400 - Add your own review/rating

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• Bacterial Endocarditis Prevention
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• Legionella Pneumonia
• Lyme Disease
• Lymphogranuloma Venereum
• Mycoplasma Pneumonia
• Nongonococcal Urethritis
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• Pemphigoid
• Pertussis
• Pharyngitis
• Pneumonia
• Rheumatic Fever Prophylaxis
• Skin Infection
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primaquine

PRIM-a-kwin

Oral route(Tablet)

Warning: Physicians should completely familiarize themselves with the complete contents of this leaflet before prescribing primaquine phosphate .

Available Dosage Forms:

• Tablet

Therapeutic Class: Antimalarial

Chemical Class: Aminoquinoline

Uses For primaquine

Primaquine belongs to the group of medicines called antiprotozoals. It is used in the treatment of malaria, a red blood cell infection transmitted by the bite of a mosquito.

Malaria transmission occurs in large areas of Central and South America, Hispaniola, sub-Saharan Africa, the Indian subcontinent, Southeast Asia, the Middle East, and Oceania. Country-specific information on malaria can be obtained from the Centers for Disease Control and Prevention (CDC), or from the CDC's web site at http://www.cdc.gov/travel/yellowbk.

Primaquine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, primaquine is used in certain patients with the following medical condition:

• Pneumocystis carinii pneumonia (PCP)

Before Using primaquine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For primaquine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to primaquine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Children should avoid traveling to areas where there is a chance of getting malaria, unless they can take effective antimalarial medicines such as primaquine.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of primaquine in the elderly with use in other age groups.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking primaquine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using primaquine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Aurothioglucose


• Levomethadyl

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of primaquine. Make sure you tell your doctor if you have any other medical problems, especially:

• Family or personal history of favism or hemolytic anemia or


• Glucose-6-phosphate dehydrogenase (G6PD) deficiency or


• Nicotinamide adenine dinucleotide (NADH) methemoglobin reductase deficiency—Patients with any of these medical problems who take primaquine may have an increased chance of side effects affecting the blood.

Proper Use of primaquine

If primaquine upsets your stomach, it may be taken with meals or with antacids. If stomach upset (nausea, vomiting, or stomach pain) continues, check with your doctor.

If you are taking primaquine for malaria, keep taking it for the full time of treatment to help prevent or completely clear up the infection. Do not miss any doses.

Dosing

The dose of primaquine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of primaquine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For malaria:
  
  • For oral dosage form (tablets):
    
    • Adults and older children: 15 milligrams (mg) once a day for 14 days.
    
    
    • Younger children: Dose is based on body weight and must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of primaquine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using primaquine

Your doctor should check your progress at regular visits to make sure that primaquine is not causing blood problems.

primaquine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Back, leg, or stomach pains


• dark urine


• fever


• loss of appetite


• pale skin


• unusual tiredness or weakness

Less common

• Bluish fingernails, lips, or skin


• difficulty breathing


• dizziness or lightheadedness

Rare

• Sore throat and fever

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Cramps


• nausea or vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: primaquine side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More primaquine resources

• Primaquine Side Effects (in more detail)
• Primaquine Dosage
• Primaquine Use in Pregnancy & Breastfeeding
• Primaquine Drug Interactions
• Primaquine Support Group
• 0 Reviews for Primaquine - Add your own review/rating

• primaquine Concise Consumer Information (Cerner Multum)


• Primaquine MedFacts Consumer Leaflet (Wolters Kluwer)


• Primaquine Prescribing Information (FDA)


• Primaquine Phosphate Monograph (AHFS DI)

Compare primaquine with other medications

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• Pneumocystis Pneumonia

Phenazopyridine Hydrochloride

Class: Antipruritics and Local Anesthetics
VA Class: GU100
CAS Number: 136-40-3
Brands: Azo-Dine, Azo-Gesic, Azo-Natural, Azo-Standard, Baridium, Prodium, Pyridium, Pyridium Plus, Re-Azo, UTI Relief

Introduction

Analgesic or local anesthetic; an azo dye.^a

Uses for Phenazopyridine Hydrochloride

Urinary Tract Mucosal Anesthesia or Analgesia

Symptomatic relief of pain, burning, urgency, frequency, and other discomforts resulting from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.^c

Use should not delay definitive diagnosis and treatment of cause; not a substitute for specific surgery or anti-infective therapy.^a

Used in combination with appropriate anti-infective agents for initial treatment (first 2 days) of uncomplicated urinary tract infections when pain, burning, or urgency relief is needed.^{a c} However, there is lack of evidence that such combinations provide greater benefit than an anti-infective agent alone after 2 days;^a continue treatment after 2 days with anti-infective agent alone.^a

Also may be used for self-medication for the symptomatic relief of minor pain, urgency, frequency, and burning on urination.^a

Phenazopyridine Hydrochloride Dosage and Administration

Administration

Administer orally after meals.^a

Dosage

Available as phenazopyridine hydrochloride; dosage expressed in terms of the salt.^c

Pediatric Patients

Urinary Tract Mucosal Anesthesia or Analgesia

Relief of Irritation Due to Trauma, Surgery, Endoscopic Procedures, or the Passage of Sounds or Catheters

Oral

12 mg/kg daily, in 3 divided doses.^a

Discontinue when pain and discomfort are relieved, usually after 3–15 days.^a

Relief of Irritation Due to Infection

Oral

12 mg/kg daily, in 3 divided doses, for no more than 2 days; use in combination with an anti-infective agent and then continue therapy with anti-infective agent alone.^{a c}

Adults

Urinary Tract Mucosal Anesthesia or Analgesia

Relief of Irritation Due to Trauma, Surgery, Endoscopic Procedures, or the Passage of Sounds or Catheters

Oral

Usually, 200 mg 3 times daily.^{a c}

Discontinue when pain and discomfort are relieved, usually after 3–15 days.^a

Relief of Irritation Due to Infection

Oral

Usually, 200 mg 3 times daily for no more than 2 days; use in combination with an anti-infective agent and then continue therapy with anti-infective agent alone.^{a c}

Self-Medication

Oral

190 mg 3 times daily for up to 2 days.^a

Consult clinician if symptoms persist for >2 days.^a

Prescribing Limits

Pediatric Patients

Urinary Tract Anesthesia or Analgesia

Relief of Irritation Due to Infection

Oral

Maximum 12 mg/kg daily, in 3 divided doses, for no more than 2 days.^{a c}

Adults

Urinary Tract Anesthesia or Analgesia

Relief of Irritation Due to Infection

Oral

Maximum 200 mg 3 times daily for no more than 2 days.^{a c}

Self-Medication

Oral

Maximum 190 mg 3 times daily for no more than 2 days.^a

Cautions for Phenazopyridine Hydrochloride

Contraindications

• 
  

  Impaired renal function,^c glomerulonephritis, uremia, or pyelonephritis during pregnancy.^a

  
  


• 
  

  Severe hepatitis.^a

  
  


• 
  

  Known hypersensitivity to phenazopyridine or any ingredient in the formulation.^c

  
  

Warnings/Precautions

General Precautions

Skin and/or Sclerae Discoloration

Discontinue if yellowish color of the skin or sclerae occurs (may indicate accumulation resulting from renal impairment).^a

Urine Discoloration

Urine may become orange to red in color, and may stain fabric; remove stains by soaking fabric in a 0.25% sodium dithionate or sodium hydrosulfite solution.^a

Self-medication

Discontinue and consult a clinician if pain and discomfort persist for longer than 2 days.^a

Use of Fixed Combination

When used in fixed combination with other agents, consider the cautions, precautions, and contraindications associated with the concomitant agents.

Specific Populations

Pregnancy

Category B.^{b c}

Lactation

Not known whether phenzopyridine or metabolites are distributed into milk.^{a b c}

Hepatic Impairment

Contraindicated in severe hepatic impairment.^a

Renal Impairment

Possible accumulation of phenazopyridine; use is contraindicated.^a

Interactions for Phenazopyridine Hydrochloride

Specific Laboratory Tests

Test	Interaction	Comments
Spectrometry or color reaction urinalysis; phenolsulfonphthalein (PSP) excretion test of kidney function.		Butanol may be used to extract phenazopyridine from the final alkaline urine dilution to give accurate resultsa
Urinary glucose tests: glucose oxidase reagent (Clinistix, Tes-Tape)	Delayed reactions with glucose oxidase reagent may be interpreted as false-negative reactions; occasional false-positive tests occur with Tes-Tapea	Cupric sulfate (Clinitest) is not affecteda
Urinary bilirubin tests (e.g., Ictotest)	May give false-positive results for the foam test and atypical color reactions with p-nitrobenzene diazonium p-toluene sulfonate reagent (Ictotest)a
Urinary ketone tests using sodium nitroprusside (Acetest, Ketostix) or Gerhardt ferric chloride	May produce interfering colorsa	Prevent by adding a small amount of sodium dithionate to urine before performing the testsa
Urinary protein tests	May discolor bromophenol blue test areas of commercial reagent strips and interfere with the nitric acid ring testa	Sulfosalicylic acid and heat-acetic acid tests are unaffecteda
Determination of urinary steroids	May interfere by affecting absorbancy in the modified Glenn-Nelson method of 17-hydroxycorticosteroid determination and the Holtorff-Koch modification of the Zimmerman reaction for determining 17-ketosteroidsa
Urinary urobilinogen determinations (Ehrlich’s reagent)	Color interferencea
Spectrophotofluorimetric screening tests and assays for porphyrins	May produce falsely elevated readingsa

Phenazopyridine Hydrochloride Pharmacokinetics

Pharmacokinetic properties have not been determined.^a

Distribution

Extent

Trace amounts may enter the CSF.^a

Trace amounts may cross the placenta; not known if distributed into milk.^a

Elimination

Metabolism

May be metabolized in the liver and other body tissues; metabolites not identified.^a

Elimination Route

Excreted principally in urine as unchanged drug (up to 65%); small amounts excreted in feces.^a

Stability

Storage

Oral

Tablets

Tight containers at 15–30°C.^a

ActionsActions

• 
  

  Exerts analgesic or local anesthetic action on the urinary tract mucosa; precise mechanism of action is not known.^a

  
  


• 
  

  Little or no antibacterial activity in the urine.^a

  
  

Advice to Patients

• 
  

  Importance of discontinuing the drug if yellowish color of the skin or sclerae occurs.^a

  
  


• 
  

  Importance of discontinuing self-medication and consulting clinician if pain and discomfort persist for longer than 2 days.^a

  
  


• 
  

  Advise that urine will become orange to red in color and may stain fabric; remove stains by soaking fabric in a 0.25% sodium dithionate or sodium hydrosulfite solution.^a

  
  


• 
  

  Potential of contact lens staining.^c

  
  


• 
  

  Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs.^a

  
  


• 
  

  Importance of possible interference with urinary glucose or ketone tests.^a

  
  


• 
  

  Importance of women informing their clinicians if they are or plan to become pregnant or plan to breast-feed.^a

  
  


• 
  

  Importance of informing patients of other important precautionary information. (See Cautions.)

  
  

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Phenazopyridine Hydrochloride

Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Oral	Tablets	95 mg	Azo-Gesic	Major, United Research
			Azo-Standard	PolyMedica
			Prodium	Requa
		97 mg	Re-Azo	Reese
		97.2 mg	Azo-Dine	Republic
			Azo-Natural	Cemco
			Baridium	Pfeiffer
			UTI Relief	Consumers Choice
		100 mg*	Pyridium	Warner Chilcott
		200 mg*	Pyridium	Warner Chilcott

* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name

Phenazopyridine Hydrochloride Combinations

Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Oral	Tablets	150 mg with Butabarbital 15 mg, and Hyoscyamine Hydrobromide 0.3 mg*	Pyridium Plus (with parabens)	Warner-Chilcott

Comparative Pricing

This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 03/2011. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.

Phenazopyridine HCl 100MG Tablets (QUALITEST): 30/$13.99 or 90/$41.13

Phenazopyridine HCl 200MG Tablets (AMNEAL PHARMACEUTICALS): 30/$20.44 or 60/$29.88

Pyridium 100MG Tablets (WARNER CHILCOTT PROF PROD DIV): 30/$35.99 or 90/$90.27

Pyridium 200MG Tablets (WARNER CHILCOTT PROF PROD DIV): 30/$64.99 or 90/$175.97

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions September 2005. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

References

a. AHFS drug information 2004. McEvoy GK, ed. Phenazopyridine. Bethesda, MD: American Society of Health-System Pharmacists; 2004:3413-4.

b. Briggs GC, Freeman RK, Yaffee SJ. Drugs in pregnancy and lactation. 6th ed. Phenazopyridine. Philadelphia, PA: Lippincott, Williams & Wilkins; 2002: 1093-4/p.

c. Amide Pharmaceuticals. Phenazopyridine hydrochloride tablets prescribing information. Little Falls, NJ; 1998:Jun.

More Phenazopyridine Hydrochloride resources

• Phenazopyridine Hydrochloride Side Effects (in more detail)
• Phenazopyridine Hydrochloride Dosage
• Phenazopyridine Hydrochloride Use in Pregnancy & Breastfeeding
• Drug Images
• Phenazopyridine Hydrochloride Drug Interactions
• Phenazopyridine Hydrochloride Support Group
• 18 Reviews for Phenazopyridine Hydrochloride - Add your own review/rating

• Azo-Gesic Advanced Consumer (Micromedex) - Includes Dosage Information


• Azo-Gesic MedFacts Consumer Leaflet (Wolters Kluwer)


• Pyridium Consumer Overview

Compare Phenazopyridine Hydrochloride with other medications

• Dysuria
• Interstitial Cystitis

Theraflu Warming Relief Daytime Multi-Symptom Cold

Generic Name: acetaminophen, dextromethorphan, and phenylephrine (a SEET a MIN of fen, DEX troe me THOR fan, and FEN il EFF rin)

Brand Names: Comtrex Cold & Cough, Daytime, Flu & Severe Cold & Cough Daytime Powder, Mapap Cold Formula, Theraflu Daytime Severe Cold & Cough, Theraflu Multi-Symptom Severe Cold, Theraflu Nighttime Severe Cold & Cough, Theraflu Warming Relief Daytime Multi-Symptom Cold, Theraflu Warming Severe Cold Daytime, Tylenol Children's Plus Cold & Cough, Tylenol Cold Multi-Symptom Daytime

What is Theraflu Warming Relief Daytime Multi-Symptom Cold (acetaminophen, dextromethorphan, and phenylephrine)?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, dextromethorphan, and phenylephrine is used to treat headache, fever, body aches, cough, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, and phenylephrine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about this medicine?

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What should I discuss with my healthcare provider before taking this medicine?

Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take acetaminophen, dextromethorphan, and phenylephrine if you have:

• 
  

  liver disease, cirrhosis, or a history of alcoholism;

  
  


• 
  

  diabetes;

  
  


• 
  

  glaucoma;

  
  


• 
  

  diabetes;

  
  


• 
  

  epilepsy or other seizure disorder;

  
  


• 
  

  enlarged prostate or urination problems;

  
  


• 
  

  pheochromocytoma (an adrenal gland tumor); or

  
  


• 
  

  cough with mucus, or cough caused by emphysema or chronic bronchitis.

  
  

It is not known whether acetaminophen, dextromethorphan, and phenylephrine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant. Acetaminophen, dextromethorphan, and phenylephrine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Artificially sweetened cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

How should I take this medicine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

Dissolve one packet of the powder in at least 4 ounces of water. Stir this mixture and drink all of it right away.

Do not take for longer than 7 days in a row. Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days. Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking this medicine?

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen.

This medicine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. chest pain, fast, slow, or uneven heart rate; Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  chest pain, fast, slow, or uneven heart rate;

  
  


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  severe dizziness, feeling like you might pass out;

  
  


• 
  

  mood changes, confusion, hallucinations;

  
  


• 
  

  tremor, seizure (convulsions);

  
  


• 
  

  fever;

  
  


• 
  

  urinating less than usual or not at all;

  
  


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  nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or

  
  


• 
  

  nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  


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  dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

  
  

Less serious side effects may include:

• 
  

  dizziness, weakness;

  
  


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  mild headache;

  
  


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  mild nausea, diarrhea, upset stomach;

  
  


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  dry mouth, nose, or throat;

  
  


• 
  

  feeling nervous, restless, irritable, or anxious; or

  
  


• 
  

  sleep problems (insomnia).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect this medicine?

Ask a doctor or pharmacist if it is safe for you to take this medicine if you are also using any of the following drugs:

• 
  

  leflunomide (Arava);

  
  


• 
  

  tapentadol (Nucynta);

  
  


• 
  

  an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;

  
  


• 
  

  an antidepressant;

  
  


• 
  

  birth control pills or hormone replacement therapy;

  
  


• 
  

  blood pressure medication;

  
  


• 
  

  cancer medicine;

  
  


• 
  

  cholesterol-lowering medications such as Lipitor, Niaspan, Zocor, Vytorin, and others;

  
  


• 
  

  gout or arthritis medications (including gold injections);

  
  


• 
  

  HIV/AIDS medication;

  
  


• 
  

  medicines to treat psychiatric disorders;

  
  


• 
  

  migraine headache medicine;

  
  


• 
  

  an NSAID such as Advil, Aleve, Arthrotec, Cataflam, Celebrex, Indocin, Motrin, Naprosyn, Treximet, Voltaren, others; or

  
  


• 
  

  seizure medication.

  
  

This list is not complete and other drugs may interact with acetaminophen, dextromethorphan, and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Theraflu Warming Relief Daytime Multi-Symptom Cold resources

• Theraflu Warming Relief Daytime Multi-Symptom Cold Use in Pregnancy & Breastfeeding
• Theraflu Warming Relief Daytime Multi-Symptom Cold Drug Interactions
• 0 Reviews for Theraflu Warming Relief Daytime Multi-Symptom Cold - Add your own review/rating

• Tylenol Cold Multi-Symptom Daytime Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Theraflu Warming Relief Daytime Multi-Symptom Cold with other medications

• Cold Symptoms
• Cough
• Cough and Nasal Congestion
• Nasal Congestion
• Pain/Fever
• Sinus Symptoms
• Tonsillitis/Pharyngitis

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, dextromethorphan, and phenylephrine.